Article
Genetic and environmental factors determining the development of Creutzfeldt-Jakob disease in Libyan Jews.
Neuroepidemiology - 1 Jan 1991
Chapman J, Korczyn A D
Abstract excerpt
The cluster of Creutzfeldt-Jakob disease (CJD) among Jews of Libyan origin is one of the largest in the world. A number of hypotheses have been proposed to account for this cluster, the most prevalent but unsubstantiated hypothesis being that a transmissible agent was ingested in the form of scrapie-infected sheep brains. It has, however, been shown that a modified host protein encoded by the gene specifying the...
Topics
- Cluster Analysis
- Creutzfeldt-Jakob Syndrome
- DNA
- Humans
- Jews
- Libya
- Mutation
- Polymerase Chain Reaction
