Article
Rapidly progressive Creutzfeldt-Jakob disease in patients with Familial Mediterranean Fever.
European journal of neurology - 1 Jun 2010
Appel S A, Chapman J, Kahana E, Rosenmann H, Prohovnik I, Pras E, Reznik-Wolf H, Cohen O S
Abstract excerpt
BACKGROUND: The largest cluster of familial Creutzfeldt-Jakob disease (fCJD) exists in Jews of Libyan origin. Familial Mediterranean fever (FMF) is an inflammatory disease also common in this population. OBJECTIVES: We hypothesized that FMF, as a pro-inflammatory condition, may affect the course of CJD. METHODS: Three hundred and seventy-two consecutive patients diagnosed clinically and genetically as CJD were...
Topics
- Adult
- Age of Onset
- Comorbidity
- Creutzfeldt-Jakob Syndrome
- Cytoskeletal Proteins
- Disease Progression
- Familial Mediterranean Fever
- Female
- Heterozygote
- Homozygote
- Humans
- Jews
- Libya
- Male
- Middle Aged