Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease.

doi:10.1098/rstb.1994.0033

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Article

Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Mar 1994

Gabizon R, Rosenman H, Meiner Z, Kahana I, Kahana E, Shugart Y, Ott J, Prusiner S B

Abstract excerpt

Various mutations in the prion protein (PrP) gene are associated with Creutzfeldt-Jakob disease (CJD), a transmissible fatal neurodegenerative disorder. Among Libyan Jews, CJD is a familial disease with an incidence about 100 times higher than the worldwide population. CJD in this community segre...

Topics

Adult
Aged
Alleles
Base Sequence
Codon
Creutzfeldt-Jakob Syndrome
DNA Primers
Female
Genetic Linkage
Genotype
Heterozygote
Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Jews

Libya

Male

Middle Aged

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 7913755
DOI: 10.1098/rstb.1994.0033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7913755-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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