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Article

Genetic analysis of interferon induced thyroiditis (IIT): evidence for a key role for MHC and apoptosis related genes and pathways.

Journal of autoimmunity - 1 Aug 2013

Hasham Alia, Zhang Weijia, Lotay Vaneet, Haggerty Shannon, Stefan Mihaela, Concepcion Erlinda, Dieterich Douglas T, Tomer Yaron

Abstract excerpt

Autoimmune thyroid diseases (AITD) have become increasingly recognized as a complication of interferon-alpha (IFNα) therapy in patients with chronic Hepatitis C virus (HCV) infection. Interferon-induced thyroiditis (IIT) can manifest as clinical thyroiditis in approximately 15% of HCV patients receiving IFNα and subclinical thyroiditis in up to 40% of patients, possibly resulting in either dose reduction or...

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Source

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Identifiers

PMID: 23683877
DOI: 10.1016/j.jaut.2013.04.002
PMCID: PMC3740053

Genes

TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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