Article
Analysis of CXCL12 3'UTR G>A polymorphism in colorectal cancer.
Oncology reports - 1 Dec 2007
Hidalgo-Pascual M, Galan J J, Chaves-Conde M, Ramírez-Armengol J A, Moreno C, Calvo E, Pelaez P, Crespo C, Ruiz A, Royo J L
Abstract excerpt
Colorectal cancer is one of the most prevalent cancers in developed countries. However, the genetic factors influencing its appearance remain far from being fully characterized. Recently, a G>A functional transition mapping the 3' untranslated region of the CXCL12 gene (rs1801157) has been found to be under-represented among rectal cancer patients when compared to colon cancer patients from a Swedish series. Here...
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