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Article

Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use.

The British journal of psychiatry : the journal of mental science - 1 Nov 2007

Zammit Stanley, Spurlock Gillian, Williams Hywel, Norton Nadine, Williams Nigel, O'Donovan Michael C, Owen Michael J

Abstract excerpt

BACKGROUND: Genetic variations might modify associations between schizophrenia and cannabis or tobacco use. AIMS: To examine whether variants within the cannabinoid receptor (CNR1) and alpha(7) nicotinic receptor (CHRNA7) genes are associated with schizophrenia, and whether these effects vary according to cannabis or tobacco use. We also examined a putative interaction between cannabis and Val(158)Met within the...

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Share to alpha7 Nicotinic Acetylcholine Receptor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to Polymorphism, Genetic

Share to Psychiatric Status Rating Scales

Share to Receptors, Nicotinic

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Source

Identifiers

PMID: 17978319
DOI: 10.1192/bjp.bp.107.036129

Genes

CHRNA7
COMT
CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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