Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The roles of kinases in familial Parkinson's disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 31 Oct 2007

Cookson Mark R, Dauer William, Dawson Ted, Fon Edward A, Guo Ming, Shen Jie

Abstract excerpt

The purpose of this mini-symposium is to discuss some of the inherited forms of Parkinson's disease (PD) in view of recent data suggesting that some of the proteins affect cellular signaling pathways. As an illustration, we shall focus on two different kinases associated with recessive and dominant forms of PD. Mutations in the mitochondrial kinase PTEN (phosphatase and tensin homolog)-induced kinase 1 (PINK1)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to PINK1 gene
Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Parkinson Disease

Share to Phosphotransferases

Share to Protein Kinases

Share to Protein Serine-Threonine Kinases

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 17978026
DOI: 10.1523/JNEUROSCI.3695-07.2007
PMCID: PMC6673380

Genes

PINK1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The roles of kinases in familial Parkinson's disease.PMID 17978026Read ↗

Kinase signaling pathways as potential targets in the treatment of Parkinson's disease.Semantic proximity Read ↗

Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1).Semantic proximity Read ↗

PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease.Semantic proximity Read ↗

Kinase signaling dysfunction in Parkinson's disease: a reverse genetic approach in Drosophila.Semantic proximity Read ↗

Activation mechanisms of the E3 ubiquitin ligase parkin.Semantic proximity Read ↗

Targeting phosphatases as the next generation of disease modifying therapeutics for Parkinson's disease.Semantic proximity Read ↗

The emerging multifaceted role of PINK1 in cancer biologySemantic proximity Read ↗

Biochemical properties of the kinase PINK1 as sensor protein for mitochondrial damage signalling.Semantic proximity Read ↗

Role of LRRK2 kinase activity in the pathogenesis of Parkinson's disease.Semantic proximity Read ↗

Emerging pathways in genetic Parkinson's disease: autosomal-recessive genes in Parkinson's disease--a common pathway?Semantic proximity Read ↗

Role of LRRK2 kinase dysfunction in Parkinson disease.Semantic proximity Read ↗

The biology and pathology of the familial Parkinson's disease protein LRRK2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.