Article
Evaluation of a commercialized in situ hybridization assay for detecting human papillomavirus DNA in tissue specimens from patients with cervical intraepithelial neoplasia and cervical carcinoma.
Journal of clinical microbiology - 1 Jan 2008
Guo Ming, Gong Yun, Deavers Michael, Silva Elvio G, Jan Yee Jee, Cogdell David E, Luthra Rajyalashmi, Lin E, Lai Hung Cheng, Zhang Wei, Sneige Nour
Abstract excerpt
To evaluate a commercialized in situ hybridization (ISH) assay for detecting human papillomavirus (HPV) DNA, we compared the ability of a new ISH probe, Inform HPV III (Ventana Medical Systems, Tucson, AZ), to that of PCR assays to detect HPV DNA in cervical tissue specimens with normal cervix (20 cases), cervical intraepithelial neoplasia (CIN; CIN 1, 27 cases; CIN 2, 28 cases; and CIN 3, 33 cases), and cervical...
Topics
- Adolescent
- Adult
- Aged
- DNA, Viral
- Female
- Genotype
- Humans
- In Situ Hybridization
- Middle Aged
- Papillomaviridae