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Article

Detection of human papillomavirus DNA in genital lesions by using a modified commercially available in situ hybridization assay.

Journal of clinical microbiology - 1 Jul 1991

Meyer M P, Markiw C A, Matuscak R R, Saker A, McIntyre-Seltman K, Amortegui A J

Abstract excerpt

A modified, commercially available DNA-DNA in situ hybridization test that uses biotinylated probes for the identification of human papillomavirus (HPV) DNA types 6/11, 16/18, and 31/33/35 was evaluated. HPV DNA was detected in 314 of 787 (40%) histologically abnormal genital biopsy specimens by using the ViraType in situ assay (Life Technologies, Gaithersburg, Md.), in which the hybridization time was increased...

Topics

Condylomata Acuminata
DNA, Viral
Evaluation Studies as Topic
Female
Genotype
Humans
Nucleic Acid Hybridization
Papillomaviridae
Tumor Virus Infections
Uterine Cervical Dysplasia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 1653262
DOI: 10.1128/jcm.29.7.1308-1311.1991
PMCID: PMC270106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1653262-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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