Article
Detection of human papillomavirus DNA in genital lesions by using a modified commercially available in situ hybridization assay.
Journal of clinical microbiology - 1 Jul 1991
Meyer M P, Markiw C A, Matuscak R R, Saker A, McIntyre-Seltman K, Amortegui A J
Abstract excerpt
A modified, commercially available DNA-DNA in situ hybridization test that uses biotinylated probes for the identification of human papillomavirus (HPV) DNA types 6/11, 16/18, and 31/33/35 was evaluated. HPV DNA was detected in 314 of 787 (40%) histologically abnormal genital biopsy specimens by using the ViraType in situ assay (Life Technologies, Gaithersburg, Md.), in which the hybridization time was increased...
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