Article
Cloning of canine myocilin cDNA and molecular analysis of the myocilin gene in Shiba Inu dogs.
Veterinary ophthalmology - 1 Jan 2000
Kato Kumiko, Sasaki Nobuo, Matsunaga Satoru, Nishimura Ryohei, Ogawa Hiroyuki
Abstract excerpt
OBJECTIVE: To identify canine myocilin cDNA and compare its sequence in glaucomatous and nonglaucomatous Shiba Inu dogs with closed and open iridocorneal angles (ICAs). PROCEDURES: Total RNA was extracted from the ciliary body of the eyes of a healthy Beagle, and the canine myocilin gene was cloned and sequenced. Of the Shiba Inu dogs tested, five were glaucomatous with closed ICA, three were nonglaucomatous with...
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