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Article

Host–pathogen protein interactions predicted by comparative modeling

26 Oct 2007

Abstract excerpt

Pathogens have evolved numerous strategies to infect their hosts, while hosts have evolved immune responses and other defenses to these foreign challenges. The vast majority of host-pathogen interactions involve protein-protein recognition, yet our current understanding of these interactions is limited. Here, we present and apply a computational whole-genome protocol that generates testable predictions of...

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PMID: 17965183
DOI: 10.1110/ps.073228407

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