In silicoprediction of host–pathogen protein interactions in melioidosis pathogenBurkholderia pseudomalleiand human reveals novel virulence factors and their targets

Abstract excerpt

The aerobic, Gram-negative motile bacillus, Burkholderia pseudomallei is a facultative intracellular bacterium causing melioidosis, a critical disease of public health importance, which is widely endemic in the tropics and subtropical regions of the world. Melioidosis is associated with high case fatality rates in animals and humans; even with treatment, its mortality is 20-50%. It also infects plants and is...

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