Article
High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India.
AIDS research and human retroviruses - 1 Oct 2007
Sen Sourav, Tripathy Srikanth P, Patil Ajit A, Chimanpure Vaishali M, Paranjape Ramesh S
Abstract excerpt
We report one or more HIV resistance mutations in 81.81% of the 33 antiretroviral treatment-experienced study participants with evidence of virologic failure, with M184V being the most commonly observed resistance mutation (69.7%). Two out of four participants with protease inhibitors (PI) experience harbored multiple PI-associated resistance mutations. No resistance mutations were observed in 22 treatment-naive...
Topics
- Adolescent
- Adult
- Anti-HIV Agents
- Antiretroviral Therapy, Highly Active
- Child
- Child, Preschool
- Drug Resistance, Viral
- Genes, pol
- HIV Infections
- HIV Protease Inhibitors