Article
Antiretroviral resistance following immunological monitoring in a resource-limited setting of western India: A cross-sectional study.
PloS one - 1 Jan 2017
Karade Santosh K, Kulkarni Smita S, Ghate Manisha V, Patil Ajit A, Londhe Rajkumar, Salvi Sonali P, Kadam Dileep B, Joshi Rajneesh K, Rewari Bharat B, Gangakhedkar Raman R
Abstract excerpt
BACKGROUND: The free antiretroviral therapy (ART) program in India still relies on the clinico-immunological monitoring for diagnosis of treatment failure. As the nucleoside reverse transcriptase inhibitor (NRTI) backbone is shared in first- and second-line regimens, accumulation of drug resistant mutations (DRMs) can compromise the efficacy of NRTI. This study was undertaken to describe the pattern of HIV DRMs...
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