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Article

Nijmegen Breakage Syndrome mutations and risk of breast cancer.

International journal of cancer - 15 Feb 2008

Bogdanova Natalia, Feshchenko Sergei, Schürmann Peter, Waltes Regina, Wieland Britta, Hillemanns Peter, Rogov Yuri I, Dammann Olaf, Bremer Michael, Karstens Johann H, Sohn Christof, Varon Raymonda, Dörk Thilo

Abstract excerpt

Mutations in the NBS1 gene have been identified as disease-causing mutations in patients with Nijmegen Breakage Syndrome (NBS), but their clinical impact on breast cancer susceptibility has remained uncertain. We determined the frequency of 2 NBS mutations, 657del5 and R215W, in two large series...

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Identifiers

PMID: 17957789
DOI: 10.1002/ijc.23168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17957789-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Nijmegen Breakage Syndrome mutations and risk of breast cancer.PMID 17957789Read ↗

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Functional deficiency of NBN, the Nijmegen breakage syndrome protein, in a p.R215W mutant breast cancer cell line.Semantic proximity Read ↗

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