Article
Molecular scanning of the human carboxypeptidase E gene for mutations in Chinese subjects with coronary atherosclerosis.
Molecular and cellular biochemistry - 1 Jan 2008
Jia En-Zhi, Wang Jie, Yang Zhi-Jian, Zhu Tie-Bing, Wang Lian-Sheng, Chen Bo, Cao Ke-Jiang, Huang Jun, Ma Wen-Zhu
Abstract excerpt
OBJECTIVE: To test the hypothesis that the identification of mutation in the carboxypeptidase E (CPE) gene which leads to marked hyperproinsulinaemia is consistent with a possible role for mutations in CPE in the development of coronary heart disease. METHODS: The study subjects consisted of 51 consecutive patients (34 males and 17 females) who will undergo coronary angiography for suspected or known coronary...
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