Article
The hsp90 molecular chaperone modulates multiple telomerase activities.
Molecular and cellular biology - 1 Jan 2008
Toogun Oyetunji A, Dezwaan Diane C, Freeman Brian C
Abstract excerpt
The Hsp90 molecular chaperone is a highly abundant eukaryotic molecular chaperone. While it is understood that Hsp90 modulates a significant number of proteins, the mechanistic contributions made by Hsp90 to a client protein typically are not well understood. Here we investigate the yeast Hsp90 regulatory roles with telomerase. Telomerase lengthens chromosome termini by specifically associating with...
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