Article
Low-density lipoprotein receptor-related protein-5 C/T polymorphism in exon 18 is associated with C peptide and proinsulin levels in control women and patients with polycystic ovary syndrome.
Fertility and sterility - 1 Sept 2008
Bendlova Bela, Vankova Marketa, Zajickova Katerina, Hill Martin, Zemanova Adela, Cibula David, Vejrazkova Daniela, Lukasova Petra, Vcelak Josef, Vondra Karel, Vrbikova Jana
Abstract excerpt
OBJECTIVE: To assess the previously unstudied potential role of C/T (A1330V) polymorphism of the low-density lipoprotein receptor-related protein-5 gene in insulin sensitivity and secretion in polycystic ovary syndrome. The low-density lipoprotein receptor-related protein-5 gene has been found to play a role in determining insulin secretion in animal models. DESIGN: Case-control study. SETTING: Tertiary...
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