Article
GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling.
Proceedings of the National Academy of Sciences of the United States of America - 30 Oct 2007
Johnston Christopher A, Taylor J Philip, Gao Yajun, Kimple Adam J, Grigston Jeffrey C, Chen Jin-Gui, Siderovski David P, Jones Alan M, Willard Francis S
Abstract excerpt
Heterotrimeric G protein signaling is important for cell-proliferative and glucose-sensing signal transduction pathways in the model plant organism Arabidopsis thaliana. AtRGS1 is a seven-transmembrane, RGS domain-containing protein that is a putative membrane receptor for d-glucose. Here we show, by using FRET, that d-glucose alters the interaction between the AtGPA1 and AtRGS1 in vivo. AtGPA1 is a unique...
Topics
- Arabidopsis
- Arabidopsis Proteins
- GTP-Binding Protein alpha Subunits
- GTPase-Activating Proteins
- Glucose
- Heterotrimeric GTP-Binding Proteins
- Kinetics
- Mutation
- Protein Subunits
- RGS Proteins