Article
Dissecting Arabidopsis Gβ signal transduction on the protein surface.
Plant physiology - 1 Jul 2012
Jiang Kun, Frick-Cheng Arwen, Trusov Yuri, Delgado-Cerezo Magdalena, Rosenthal David M, Lorek Justine, Panstruga Ralph, Booker Fitzgerald L, Botella José Ramón, Molina Antonio, Ort Donald R, Jones Alan M
Abstract excerpt
The heterotrimeric G-protein complex provides signal amplification and target specificity. The Arabidopsis (Arabidopsis thaliana) Gβ-subunit of this complex (AGB1) interacts with and modulates the activity of target cytoplasmic proteins. This specificity resides in the structure of the interface between AGB1 and its targets. Important surface residues of AGB1, which were deduced from a comparative evolutionary...
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