Article
Genetic diversity of the gene cluster encoding longus, a type IV pilus of enterotoxigenic Escherichia coli.
Journal of bacteriology - 1 Dec 2007
Gomez-Duarte Oscar G, Chattopadhyay Sujay, Weissman Scott J, Giron Jorge A, Kaper James B, Sokurenko Evgeni V
Abstract excerpt
Enterotoxigenic Escherichia coli (ETEC) strains produce a type IV pilus named Longus. We identified a 16-gene cluster involved in the biosynthesis of Longus that has 57 to 95% identity at the protein level to CFA/III, another type IV pilus of ETEC. Alleles of the Longus structural subunit gene lngA demonstrate a diversity of 12 to 19% at the protein level with strong positive selection for point replacements and...
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