Article
QTLs identified for P3 amplitude in a non-clinical sample: importance of neurodevelopmental and neurotransmitter genes.
Biological psychiatry - 1 May 2008
Wright Margaret J, Luciano Michelle, Hansell Narelle K, Montgomery Grant W, Geffen Gina M, Martin Nicholas G
Abstract excerpt
BACKGROUND: The P3(00) event-related potential is an index of processing capacity (P3 amplitude) and stimulus evaluation (P3 latency) as well as a phenotypic marker of various forms of psychopathology where P3 abnormalities have been reported. METHODS: A genome-wide linkage scan of 400-761 autosomal markers, at an average spacing of 5-10 centimorgans (cM), was completed in 647 twins/siblings (306 families mostly...
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