Article
A mathematical model relating chromosome aberrations to cancer progression.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference - 1 Jan 2000
DiPierdomenico Julia, Ying Hao, Lin Feng, Heng Henry H Q
Abstract excerpt
The main focus of this paper is to mathematically represent the dynamics of cancer evolution by studying patterns of chromosomal aberrations. A mathematical model for the progression and evolution of cancer in cultured fibroblast cells is proposed. Solution of the differential equations was performed for a continuous model by assuming variable genetic aberration pseudo reaction rate constants for each stage of...
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