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Article

Mutational analysis and homology modelling of SyrC, the aminoacyltransferase in the biosynthesis of syringomycin.

Biochemical and biophysical research communications - 14 Dec 2007

Fullone Maria Rosaria, Paiardini Alessandro, Gross Dennis C, Lu Shi-En, Fiore Alberto, Grgurina Ingeborg

Abstract excerpt

SyrC, a component of the multienzyme system of syringomycin biosynthesis, has been shown to shuttle Thr/4-Cl-Thr between the thiolation domains SyrB1-T1 and SyrE-T8,9 by transiently linking it to Cys224 in the enzyme active site. We present data on the structure-function relationship in vivo of t...

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PMID: 17945189
DOI: 10.1016/j.bbrc.2007.09.116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17945189-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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