Article
Association of CA repeat polymorphism in estrogen receptor beta gene with postmenopausal osteoporosis in Chinese.
Journal of genetics and genomics = Yi chuan xue bao - 1 Oct 2007
Geng Li, Yao Zhenwei, Yang Hongchang, Luo Jianyun, Han Lili, Lu Qi
Abstract excerpt
Postmenopausal osteoporosis (PMO) is considered a polygenic disease. The estrogen receptor beta (ESR2) gene is a candidate mediating the genetic influence on bone mass and the risk of osteoporosis. The aim of this study is to investigate the association of a cytosine-adenine (CA) repeat polymorphism in the fifth intron of the ESR2 gene with PMO in Chinese Han population. The CA repeat polymorphism was genotyped...
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