Article
The ribosomal protein genes and Minute loci of Drosophila melanogaster.
Genome biology - 1 Jan 2007
Marygold Steven J, Roote John, Reuter Gunter, Lambertsson Andrew, Ashburner Michael, Millburn Gillian H, Harrison Paul M, Yu Zhan, Kenmochi Naoya, Kaufman Thomas C, Leevers Sally J, Cook Kevin R
Abstract excerpt
BACKGROUND: Mutations in genes encoding ribosomal proteins (RPs) have been shown to cause an array of cellular and developmental defects in a variety of organisms. In Drosophila melanogaster, disruption of RP genes can result in the 'Minute' syndrome of dominant, haploinsufficient phenotypes, which include prolonged development, short and thin bristles, and poor fertility and viability. While more than 50 Minute...
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