Article
A dual biosensor for 2-alkyl-4-quinolone quorum-sensing signal molecules.
Environmental microbiology - 1 Nov 2007
Fletcher Matthew P, Diggle Stephen P, Crusz Shanika A, Chhabra Siri Ram, Cámara Miguel, Williams Paul
Abstract excerpt
Pseudomonas, Burkholderia and Alteromonas species produce diverse 2-alkyl-4-quinolones (AHQs) which inhibit the growth of bacteria, algae and phytoplankton, chelate iron, modulate mammalian host immune defences and act as quorum-sensing (QS) signal molecules. To facilitate the detection, identification and quantification of the major Pseudomonas aeruginosa AHQs 2-heptyl-3-hydroxy-4-quinolone (PQS) and...
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