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Article

Familial colorectal cancer syndrome X.

Seminars in oncology - 1 Oct 2007

Lipkin Steven M, Afrasiabi Kambiz

Abstract excerpt

In recent decades there have been significant advances in our understanding of the genes that underlie hereditary susceptibility to colorectal cancer (CRC). In 2007 it is well established that mutations in DNA repair genes (MLH1, MSH2, MSH6, MYH) and Wnt pathway signal transduction inhibitors (APC) underlie a significant percentage of hereditary CRC susceptibility. However, it also is clear that the known CRC...

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Source

Identifiers

PMID: 17920898
DOI: 10.1053/j.seminoncol.2007.07.008

Genes

APC
MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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