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Article

The -181 A/C polymorphism in the excitatory amino acid transporter-2 gene promoter affects the personality trait of reward dependence in healthy subjects.

Neuroscience letters - 5 Nov 2007

Matsumoto Yoshihiko, Suzuki Akihito, Ishii Genki, Oshino Shingo, Otani Koichi, Goto Kaoru

Abstract excerpt

There have been some animal and human data suggesting that excitatory amino acid transporter (EAAT)-2, the major subtype of EAAT, is involved in human mental function and behavior. Recently, it has been shown that the -181 A/C polymorphism in the EAAT2 gene promoter affects plasma glutamate concentrations in humans. In the present study, the association of this genetic polymorphism with personality traits was...

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Share to Excitatory Amino Acid Transporter 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 17920768
DOI: 10.1016/j.neulet.2007.09.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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