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Article

LC-MS/MS assay for protein amino acids and metabolically related compounds for large-scale screening of metabolic phenotypes.

Analytical chemistry - 1 Nov 2007

Gu Liping, Jones A Daniel, Last Robert L

Abstract excerpt

A modified LC-MS/MS method for large-scale screening of metabolic phenotypes was developed and validated. Twenty amino acids and 5 metabolically related compounds are measured within 4 min using multiple reaction monitoring (MRM) transitions selective for each compound. Separation with a short C18 column and rapid gradient using the ion-pairing reagent perfluoroheptanoic acid allows chromatographic resolution of...

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PMID: 17918906
DOI: 10.1021/ac070938b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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