Article
The localized adherence pattern of an atypical enteropathogenic Escherichia coli is mediated by intimin omicron and unexpectedly promotes HeLa cell invasion.
Cellular microbiology - 1 Feb 2008
Hernandes Rodrigo Tavanelli, Silva Rosa Maria, Carneiro Sylvia Mendes, Salvador Fábia Andréia, Fernandes Maria Cecília Di Ciero, Padovan Ana Carolina Barbosa, Yamamoto Denise, Mortara Renato Arruda, Elias Waldir Pereira, da Silva Briones Marcelo Ribeiro, Gomes Tânia Aparecida Tardelli
Abstract excerpt
Enteropathogenic Escherichia coli (EPEC) forms attaching and effacing lesions in the intestinal mucosa characterized by intimate attachment to the epithelium by means of intimin (an outer membrane adhesin encoded by eae). EPEC is subgrouped into typical (tEPEC) and atypical (aEPEC); only tEPEC carries the EAF (EPEC adherence factor) plasmid that encodes the bundle-forming pilus (BFP). Characteristically, after 3...
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