Article
Neurodevelopment in seizure-prone and seizure-resistant rat strains: recognizing conflicts in management.
Epilepsia - 1 Jan 2007
Gilby Krista L, Crino Peter, McIntyre Dan C
Abstract excerpt
Cytoarchitectural alterations during central nervous system (CNS) development are believed to underlie aberrations in brain morphology that lead to epilepsy. We have recently reported marked reductions in hippocampal and white matter volumes along with relative ventriculomegaly in a rat strain bred to be seizure-prone (FAST) compared to a strain bred to be seizure-resistant (SLOW) (Gilby et al., 2002, American...
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