Article
HLA class I polymorphisms are associated with development of infectious mononucleosis upon primary EBV infection.
The Journal of clinical investigation - 1 Oct 2007
McAulay Karen A, Higgins Craig D, Macsween Karen F, Lake Annette, Jarrett Ruth F, Robertson Faye L, Williams Hilary, Crawford Dorothy H
Abstract excerpt
Infectious mononucleosis (IM) is an immunopathological disease caused by EBV that occurs in young adults and is a risk factor for Hodgkin lymphoma (HL). An association between EBV-positive HL and genetic markers in the HLA class I locus has been identified, indicating that genetic differences in the HLA class I locus may alter disease phenotypes associated with EBV infection. To further determine whether HLA...
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