Article
Immune function in young children with previous pulmonary or miliary/meningeal tuberculosis and impact of BCG vaccination.
Pediatrics - 1 Oct 2007
Sterling Timothy R, Martire Terezinha, de Almeida Alexandre Silva, Ding Li, Greenberg David E, Moreira Lorena Alves, Elloumi Houda, Torres Angelica P V, Sant'Anna Clemax Couto, Calazans Eliane, Paraguassu Geraldo, Gebretsadik Tebeb, Shintani Ayumi, Miller Kathleen, Kritski Afranio, Lapa e Silva Jose Roberto, Holland Steven M
Abstract excerpt
OBJECTIVE: Children <5 years old are at increased risk of miliary/meningeal tuberculosis, but the immunologic factors that place them at risk are unknown. BCG vaccine protects against miliary/meningeal tuberculosis, but the mechanism of protection is unknown. We assessed for abnormalities in immune response associated with miliary/meningeal or pulmonary tuberculosis in young children. PATIENTS AND METHODS: We...
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