Article
Genetic dissection of the divergent activities of the multifunctional membrane sensor BglF.
Journal of bacteriology - 1 Dec 2007
Monderer-Rothkoff Galya, Amster-Choder Orna
Abstract excerpt
BglF catalyzes beta-glucoside phosphotransfer across the cytoplasmic membrane in Escherichia coli. In addition, BglF acts as a sugar sensor that controls expression of beta-glucoside utilization genes by reversibly phosphorylating the transcriptional antiterminator BglG. Thus, BglF can exist in two opposed states: a nonstimulated state that inactivates BglG by phosphorylation and a sugar-stimulated state that...
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