Article
A new O-antigen gene cluster has a key role in the virulence of the Escherichia coli meningitis clone O45:K1:H7.
Journal of bacteriology - 1 Dec 2007
Plainvert Céline, Bidet Philippe, Peigne Chantal, Barbe Valérie, Médigue Claudine, Denamur Erick, Bingen Edouard, Bonacorsi Stéphane
Abstract excerpt
A new highly pathogenic clone of Escherichia coli meningitis strains harboring the unusual serogroup O45 has recently emerged in France. To gain insight into the pathogenicity of this new clone, we investigated the possible role of antigen O45 in the virulence of strain S88 (O45:K1:H7), representative of this emerging clone. We first showed that the S88 O-antigen gene cluster sequence differs from that of O45 in...
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