Article
Identification of the two glycosyltransferase genes responsible for the difference between Escherichia coli O107 and O117 O-antigens.
Glycobiology - 1 Feb 2012
Wang Quan, Perepelov Andrei V, Wen Liuqing, Shashkov Alexander S, Wang Xiaoting, Guo Xi, Knirel Yuriy A, Wang Lei
Abstract excerpt
The O-antigen is one of the most variable Gram-negative cell constituents, and its specificity is important for bacterial niche adaptation. The observed diversity of O-antigen forms is mainly due to genetic variations in O-antigen gene clusters. Less common is a change of gene function due to nucleotide substitution; a new instance of which is reported here. The O-antigens of E. coli O107 and O117 have similar...
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