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Article

Polymorphisms in thrombophilia and renin-angiotensin system pathways, preterm delivery, and evidence of placental hemorrhage.

American journal of obstetrics and gynecology - 1 Sept 2009

Gargano Julia Warner, Holzman Claudia B, Senagore Patricia K, Reuss M Lynne, Pathak Dorothy R, Friderici Karen H, Jernigan Katherine, Fisher Rachel

Abstract excerpt

OBJECTIVE: The purpose of this study was to analyze functional polymorphisms in candidate genes (methylenetetrahydrofolate reductase [MTHFR]677C>T, MTHFR1298A>C, factor 5 1691G>A [FVL], and angiotensinogen (AGT)-6G>A) in relation to a hypothesized placental hemorrhage pathway to preterm delivery (PTD). STUDY DESIGN: We assessed maternal genotypes, pregnancy outcomes, and placental pathologic evidence among 560...

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Source

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Identifiers

PMID: 19733287
DOI: 10.1016/j.ajog.2009.05.060
PMCID: PMC3018335

Genes

AGT
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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