Article
Lack of association between HLA-DR antigens and sleep-onset REM periods in major depression.
Biological psychiatry - 15 Dec 1991
Staner L, Bouillon E, Andrien M, Dupont E, Mendlewicz J
Abstract excerpt
Narcolepsy is the disease disclosing the strongest association with the HLA system. Almost 100% of cases are associated with HLA-DR2 antigen. Moreover, narcolepsy is often characterized by the occurrence of sleep-onset REM (SOREM) periods. SOREM has also been demonstrated in major depression. To...
Topics
- Adult
- Depressive Disorder
- Female
- Gene Frequency
- Genetic Markers
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Male
- Middle Aged
- Phenotype
- Reaction Time
- Sleep, REM