Article
Identification and expression analysis of novel LAGE-1 alleles with single nucleotide polymorphisms in cancer patients.
Journal of cancer research and clinical oncology - 1 Apr 2008
Shao Yi, Sun Zhen-Yuan, Sun Shi-Wei, Zhao Yi, Sin Wan Yee, Yuan Yan-Hua, Simpson Andrew J, Old Lloyd J, Sang Xin-Ting, Mao Yi-Lei, Xie Yong, Huang Jie-Fu, Zhao Hai-Tao
Abstract excerpt
OBJECTIVE: The purpose of this study is to identify single nucleotide polymorphisms (SNPs) in the coding region alleles of the X chromosomal LAGE-1 gene, and investigate the frequency of such SNPs in both cancer patients and healthy controls, and thus determine the potential significance of these SNPs with respect to cancer vaccine therapy. METHODS: In this study, different mRNAs transcribed from the LAGE-1 gene...
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