Article
Long noncoding RNAs as potential biomarkers in gastric cancer: Opportunities and challenges.
Cancer letters - 1 Feb 2016
Yang Ziguo, Guo Xiaobo, Li Guimei, Shi Yulong, Li Leping
Abstract excerpt
Gastric cancer (GC) is a major threat to human health, and its prognosis is poor due to the lack of appropriate biomarkers. LncRNAs are a group of non-protein-coding RNAs that regulate gene expression at the transcriptional or posttranscriptional level. LncRNAs play essential roles in GC initiation and development in the same way as oncogenes or tumour suppressor genes. Recent investigations have revealed that...
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