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Article

Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief.

Clinical pharmacology and therapeutics - 1 Apr 2008

Campa D, Gioia A, Tomei A, Poli P, Barale R

Abstract excerpt

The pharmacokinetics and pharmacodynamics of morphine are under the control of several polymorphic genes, which can account for part of the observed interindividual variation in pain relief. We focused on two such genes: ABCB1/MDR1, a major determinant of morphine bioavailability, and OPRM1, whic...

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Share to Analgesics, Opioid
Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Morphine

Share to Receptors, Opioid, mu

Source

Identifiers

PMID: 17898703
DOI: 10.1038/sj.clpt.6100385

Genes

ABCB1
OPRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17898703-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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