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Faced with inequality: chicken do not have a general dosage compensation of sex-linked genes

20 Sept 2007

Abstract excerpt

BACKGROUND: The contrasting dose of sex chromosomes in males and females potentially introduces a large-scale imbalance in levels of gene expression between sexes, and between sex chromosomes and autosomes. In many organisms, dosage compensation has thus evolved to equalize sex-linked gene expression in males and females. In mammals this is achieved by X chromosome inactivation and in flies and worms by up- or...

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PMID: 17883843
DOI: 10.1186/1741-7007-5-40

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