Article
Gastro-intestinal stromal tumour--role of CD117 in diagnosis and management.
Indian journal of pathology & microbiology - 1 Apr 2007
Paul Prabir Chandra, Chakraborty Jayati, Kundu Debabrata, Sarkar Ranu
Abstract excerpt
Gastro-intestinal stromal tumours (GIST) are a biologically distinct heterogenous group of tumours of the gut. They are said to arise from interstitial cells of Cajal in gut wall. The turnour results from mutation of c-kit gene which codes for CD117 containing tyrosine kinase receptor of Cajal ce...
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