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Article

Basonuclin regulates a subset of ribosomal RNA genes in HaCaT cells.

PloS one - 19 Sept 2007

Zhang Shengliang, Wang Junwen, Tseng Hung

Abstract excerpt

Basonuclin (Bnc1), a cell-type-specific ribosomal RNA (rRNA) gene regulator, is expressed mainly in keratinocytes of stratified epithelium and gametogenic cells of testis and ovary. Previously, basonuclin was shown in vitro to interact with rRNA gene (rDNA) promoter at three highly conserved sites. Basonuclin's high affinity binding site overlaps with the binding site of a dedicated and ubiquitous Pol I...

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Identifiers

PMID: 17878937
DOI: 10.1371/journal.pone.0000902
PMCID: PMC1975673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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