Article
Circadian organization of tau mutant hamsters: aftereffects and splitting.
Journal of biological rhythms - 1 Oct 2007
Bittman Eric L, Costello Mary K, Brewer Judy McKinley
Abstract excerpt
Homozygous tau mutant (tau(ss)) hamsters show an extremely short (20 h) circadian period (tau) that is attributable to altered enzymatic activity of casein kinase 1epsilon. It has been proposed that coupling of constituent circadian oscillators is strengthened in tau(ss) hamsters, explaining their tendency to show strong resetting after prolonged exposure to constant darkness. To evaluate further the circadian...
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