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Article

A feline immunodeficiency virus vif-deletion mutant remains attenuated upon infection of newborn kittens.

The Journal of general virology - 1 Oct 2007

Shen Xiaoying, Leutenegger Christian M, Stefano Cole Kelly, Pedersen Niels C, Sparger Ellen E

Abstract excerpt

This report characterizes lentivirus attenuation associated with a vif mutation by inoculation of newborn kittens with a vif-deleted feline immunodeficiency virus provirus plasmid (FIV-pPPRDeltavif). Virus in peripheral blood, antiviral antibody or CD4 T-cell count alterations were not detected in kittens inoculated with FIV-pPPRDeltavif plasmid, with the exception of one kitten that demonstrated FIV Gag antibody...

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Share to Animals, Newborn
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD4-Positive T-Lymphocytes

Share to Gene Products, vif

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Share to Immunodeficiency Virus, Feline

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Source

Identifiers

PMID: 17872533
DOI: 10.1099/vir.0.83268-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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