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Article

Cell-type specific induction of tryptophan hydroxylase-2 transcription by calcium mobilization.

Journal of neurochemistry - 1 Dec 2007

Remes Lenicov Federico, Lemonde Sylvie, Czesak Margaret, Mosher Tera M, Albert Paul R

Abstract excerpt

Alterations in brain serotonin levels are implicated in major depression and are regulated by tryptophan hydroxylase-2 (TPH2). To study its regulation, we measured TPH2 RNA by quantitative RT-PCR in differentiated serotonergic rat raphe RN46A and GH4C1 pituitary cells, which express TPH2. Upon ca...

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Source

Identifiers

PMID: 17868301
DOI: 10.1111/j.1471-4159.2007.04903.x

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17868301-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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