Article
MMP-1 (collagenase-1) expression in primary colorectal cancer and its metastases.
Scandinavian journal of gastroenterology - 1 Dec 2007
Bendardaf Riyad, Buhmeida Abdelbaset, Ristamäki Raija, Syrjänen Kari, Pyrhönen Seppo
Abstract excerpt
OBJECTIVE: The role of MMP-1 (collagenase-1) in the development of a metastatic phenotype in colorectal cancer (CRC) has not been fully studied. The aim of this study was to investigate the mechanisms involved in the dissemination of CRC by examining the expression of MMP-1 in the primary tumours and their metastases, with special reference to standard clinicopathological features and disease outcome. MATERIAL...
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