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Article

FGF-4 increases in vitro expansion rate of human adult bone marrow-derived mesenchymal stem cells.

Growth factors (Chur, Switzerland) - 1 Apr 2007

Farré Jordi, Roura Santiago, Prat-Vidal Cristina, Soler-Botija Carolina, Llach Anna, Molina Cristina E, Hove-Madsen Leif, Cairó Jordi J, Gòdia Francesc, Bragós Ramon, Cinca Juan, Bayes-Genis Antoni

Abstract excerpt

Human bone marrow-derived mesenchymal stem cells (MSCs) exhibit limited in vitro growth. Fibroblast growth factors (FGFs) elicit a variety of biological responses, such as cell proliferation, differentiation and migration. FGF-4 represents one of the FGFs with the highest cell mitogenic activity. We studied the effect of FGF-4 on MSCs growth and pluripotency. MSCs duplication time (Td) was significantly reduced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17852409
DOI: 10.1080/08977190701345200

Genes

MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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